SALVINORIN A (active compound in Salvia divinorum)
Physical: C23H28O8 molecular weight 432.47; C 63.88% H 6.53% O 29.6%
Isolation: Ortega, Journal of the Chemical Society I: 2505, 1982; Valdés, Journal of Organic Chemistry 49: 4716,
1984 (Salvia divinorum)
Synthesis: none reported; configuration: Koreeda, Chemical Letters 2015, 1990
Chemistry: colorless, orthorhombic crystals from methanol, mp 238-240°; 242-244° from ethanol; SALVINORIN B
[divinorin B; C21H26O7 molecular weight 390.23; C 64.58% H 6.71% O 28.70%] cryst.
From methanol, mp 213-216°; stereochem. Koreeda, Chemical Letters 2015, 1990
Pharmacology: psychoptic above 200 mcg vaporized (Siebert, J. Ethnopharm. 43: 53, 1994); 100 mcg Sublingual human
threshold (Ott, Curare 18: 103, 1995); SALVINORIN B inactive in mice; human pharmacology unknown
Legal Status: not controlled W A R N I N G S